DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1

DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1

Abstract Background DNMT3A mutations are frequently discovered in acute myeloid leukemia (AML), associated with poor outcome. Recently, a relapse case report of AML extramedullary disease has showed that AML cells harboring DNMT3A variation were detected in the cerebral spinal fluid. However, whethe...

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Bibliographic Details
Main Authors: Jie Xu, Wu Zhang, Xiao-Jing Yan, Xue-Qiu Lin, Wei Li, Jian-Qing Mi, Jun-Min Li, Jiang Zhu, Zhu Chen, Sai-Juan Chen
Format: Article
Language:English
Published: BMC 2016-10-01
Series:Journal of Hematology & Oncology
Subjects:
DNMT3A mutation
Acute myeloid leukemia
Extramedullary infiltration
TWIST1
Online Access:http://link.springer.com/article/10.1186/s13045-016-0337-3

Internet

http://link.springer.com/article/10.1186/s13045-016-0337-3

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