Connecting genetics and gene expression data for target prioritisation and drug repositioning

Connecting genetics and gene expression data for target prioritisation and drug repositioning

Abstract Developing new drugs continues to be a highly inefficient and costly business. By repurposing an existing compound for a different indication, drug repositioning offers an attractive alternative to traditional drug discovery. Most of these approaches work by matching transcriptional disease...

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Bibliographic Details
Main Authors: Enrico Ferrero, Pankaj Agarwal
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BioData Mining
Subjects:
Drug discovery
Drug repositioning
Genomics
Transcriptomics
Online Access:http://link.springer.com/article/10.1186/s13040-018-0171-y

Internet

http://link.springer.com/article/10.1186/s13040-018-0171-y

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