Sirt6 Deacetylase: A Potential Key Regulator in the Prevention of Obesity, Diabetes and Neurodegenerative Disease

Sirt6 Deacetylase: A Potential Key Regulator in the Prevention of Obesity, Diabetes and Neurodegenerative Disease

Sirtuins, NAD + dependent proteins belonging to class III histone deacetylases, are involved in regulating numerous cellular processes including cellular stress, insulin resistance, inflammation, mitochondrial biogenesis, chromatin silencing, cell cycle regulation, transcription, and apoptosis. Of t...

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Bibliographic Details
Main Authors: Swapnil Raj, Liston Augustine Dsouza, Shailendra Pratap Singh, Abhinav Kanwal
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
drug discovery
epigenetics
diseases
modulators
Sirt6
sirtuins
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.598326/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.598326/full

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