Identifying Critical States of Complex Diseases by Single-Sample Jensen-Shannon Divergence

MotivationThe evolution of complex diseases can be modeled as a time-dependent nonlinear dynamic system, and its progression can be divided into three states, i.e., the normal state, the pre-disease state and the disease state. The sudden deterioration of the disease can be regarded as the state tra...

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Bibliographic Details
Main Authors: Jinling Yan, Peiluan Li, Rong Gao, Ying Li, Luonan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.684781/full