Mucoadhesive Vaginal Discs based on Cyclodextrin and Surfactants for the Controlled Release of Antiretroviral Drugs to Prevent the Sexual Transmission of HIV

Mucoadhesive Vaginal Discs based on Cyclodextrin and Surfactants for the Controlled Release of Antiretroviral Drugs to Prevent the Sexual Transmission of HIV

The strategies for developing vaginal microbicides to protect women against human immunodeficiency virus (HIV) sexual transmission are constantly changing. Although the initial dosage forms required daily administration to offer effective protection, the trend then moved towards sustained-release do...

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Bibliographic Details
Main Authors: Fernando Notario-Pérez, Araceli Martín-Illana, Raúl Cazorla-Luna, Roberto Ruiz-Caro, Aitana Tamayo, Juan Rubio, Veiga María-Dolores
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
coitally-dependent microbicide
dapivirine
freeze-dried gels
human immunodeficiency virus
2-hydroxypropyl-β-cyclodextrin
mucoadhesive vaginal discs
Online Access:https://www.mdpi.com/1999-4923/12/4/321

Internet

https://www.mdpi.com/1999-4923/12/4/321

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