Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas.

We previously found that a directional movement of the raft component GD3 towards mitochondria, by its association with microtubules, was mandatory to late apoptogenic events triggered by CD95/Fas. Since CLIPR-59, CLIP-170-related protein, has recently been identified as a microtubule binding protei...

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Bibliographic Details
Main Authors: Maurizio Sorice, Paola Matarrese, Valeria Manganelli, Antonella Tinari, Anna Maria Giammarioli, Vincenzo Mattei, Roberta Misasi, Tina Garofalo, Walter Malorni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2797139?pdf=render