Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction

In order to understand the role of formaldehyde in living systems, real-time monitoring is required. Here the authors report a genetically encoded, reaction-based formaldehyde sensor (FAsor) that enables visualisation of formaldehyde in mammalian cells and tissues.

Bibliographic Details
Main Authors: Rongfeng Zhu, Gong Zhang, Miao Jing, Yu Han, Jiaofeng Li, Jingyi Zhao, Yulong Li, Peng R. Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20754-4