Metabolism of Cryptic Peptides Derived from Neuropeptide FF Precursors: The Involvement of Insulin-Degrading Enzyme

The term “cryptome” refers to the subset of cryptic peptides with bioactivities that are often unpredictable and very different from the parent protein. These cryptic peptides are generated by proteolytic cleavage of proteases, whose identification in vivo can be very challenging. In this work, we s...

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Bibliographic Details
Main Authors: Giuseppe Grasso, Przemyslaw Mielczarek, Magdalena Niedziolka, Jerzy Silberring
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Molecular Sciences
Subjects:
IDE
Online Access:http://www.mdpi.com/1422-0067/15/9/16787