Menthol to Induce Non-shivering Thermogenesis via TRPM8/PKA Signaling for Treatment of Obesity

Increasing basal energy expenditure via uncoupling protein 1 (UCP1)-dependent non-shivering thermogenesis is an attractive therapeutic strategy for treatment of obesity. Transient receptor potential melastatin 8 (TRPM8) channel activation by cold and cold mimetics induces UCP1 transcription and prev...

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Bibliographic Details
Main Authors: Owen Davis Sanders, Jayalekshmi Archa Rajagopal, Lekshmy Rajagopal
Format: Article
Language:English
Published: Korean Society for the Study of Obesity 2021-03-01
Series:Journal of Obesity & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.7570/jomes20038