Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae.

The development of resistance to insecticides has become a classic exemplar of evolution occurring within human time scales. In this study we demonstrate how resistance to DDT in the major African malaria vector Anopheles gambiae is a result of both target-site resistance mechanisms that have introg...

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Bibliographic Details
Main Authors: Sara N Mitchell, Daniel J Rigden, Andrew J Dowd, Fang Lu, Craig S Wilding, David Weetman, Samuel Dadzie, Adam M Jenkins, Kimberly Regna, Pelagie Boko, Luc Djogbenou, Marc A T Muskavitch, Hilary Ranson, Mark J I Paine, Olga Mayans, Martin J Donnelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3968025?pdf=render