Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer

Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer

Abstract Background Human ovarian cancer specific transcript 2 (HOST2) is a long non-coding RNA (lncRNA) reported to be specifically high expressed in human ovarian cancer. However, the mechanism that how HOST2 regulates triple negative breast cancer (TNBC) need to be explored. Methods In this study...

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Bibliographic Details
Main Authors: Kaiyao Hua, Xiaochong Deng, Jiashu Hu, Changle Ji, Yunhe Yu, Jiayi Li, Xuehui Wang, Lin Fang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
HOST2
TNBC
Let-7b
STAT3
ceRNA
Online Access:http://link.springer.com/article/10.1186/s13046-020-01561-7

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http://link.springer.com/article/10.1186/s13046-020-01561-7

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