Hemolysis during cardiac surgery is associated with increased intravascular nitric oxide consumption and perioperative kidney and intestinal tissue damage

Hemolysis during cardiac surgery is associated with increased intravascular nitric oxide consumption and perioperative kidney and intestinal tissue damage

IntroductionAcute kidney injury (AKI) and intestinal injury negatively impact patient outcome after cardiac surgery. Enhanced nitric oxide (NO) consumption due to intraoperative intravascular hemolysis may play an important role in this setting. This study investigated the impact of hemolysis on pla...

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Bibliographic Details
Main Authors: Iris Catharina Vermeulen Windsant, Norbert CJ de Wit, Jonas TC Sertorio, Annemarie A van Bijnen, Yuri M Ganushchak, John H Heijmans, Jose E Tanus-Santos, Michael M Jacobs, Jos G Maessen, Wim A Buurman
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Physiology
Subjects:
Acute Kidney Injury
Cardiopulmonary Bypass
Extracorporeal Circulation
Hemolysis
Nitric Oxide
intestinal fatty acid binding protein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00340/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00340/full

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