Functional Characterization of Ubiquitin-Like Core Autophagy Protein ATG12 in Dictyostelium discoideum

Functional Characterization of Ubiquitin-Like Core Autophagy Protein ATG12 in Dictyostelium discoideum

Autophagy is a highly conserved intracellular degradative pathway that is crucial for cellular homeostasis. During autophagy, the core autophagy protein ATG12 plays, together with ATG5 and ATG16, an essential role in the expansion of the autophagosomal membrane. In this study we analyzed gene replac...

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Bibliographic Details
Main Authors: Sarah Fischer, Ramesh Rijal, Peter Frommolt, Prerana Wagle, Roman Konertz, Jan Faix, Susanne Meßling, Ludwig Eichinger
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cells
Subjects:
ATG12
ATG16
autophagy
Dictyostelium
ubiquitin-like protein
post-translational modifier
phagocytosis
pinocytosis
proteasome
ubiquitin proteasome system (UPS)
Online Access:http://www.mdpi.com/2073-4409/8/1/72

Internet

http://www.mdpi.com/2073-4409/8/1/72

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