Discovery of New Compounds Active against Plasmodium falciparum by High Throughput Screening of Microbial Natural Products.

Due to the low structural diversity within the set of antimalarial drugs currently available in the clinic and the increasing number of cases of resistance, there is an urgent need to find new compounds with novel modes of action to treat the disease. Microbial natural products are characterized by...

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Main Authors: Guiomar Pérez-Moreno, Juan Cantizani, Paula Sánchez-Carrasco, Luis Miguel Ruiz-Pérez, Jesús Martín, Noureddine El Aouad, Ignacio Pérez-Victoria, José Rubén Tormo, Víctor González-Menendez, Ignacio González, Nuria de Pedro, Fernando Reyes, Olga Genilloud, Francisca Vicente, Dolores González-Pacanowska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4703298?pdf=render