Brain renin-angiotensin system and dopaminergic cell vulnerability

Brain renin-angiotensin system and dopaminergic cell vulnerability

Although the renin-angiotensin system (RAS) was classically considered as a circulating system that regulates blood pressure, many tissues are now known to have a local RAS. Angiotensin, via type 1 receptors, is a major activator of the NADPH-oxidase complex, which mediates several key events in oxi...

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Bibliographic Details
Main Authors: Jose L Labandeira-Garcia, Pablo eGarrido-Gil, Jannette eRodriguez-Pallares, Rita eValenzuela, Ana eBorrajo, Ana I Rodríguez-Perez
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Neuroanatomy
Subjects:
Aging
Dopamine
Oxidative Stress
Parkinson
neurodegeneration
Neuroinflammation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00067/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00067/full

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