Quantitative comparison between poly(L-arginine) and poly(L-lysine) at each step of polyplex-based gene transfection using a microinjection technique
Among the well-studied polypeptide-type gene carriers, transfection efficiency is empirically known to be higher for poly(L-arginine) (PR) than poly(L-lysine) (PK). The big difference between PR and PK should be determined at one of the intracellular trafficking steps based on the different charge d...
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2012-01-01
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Series: | Science and Technology of Advanced Materials |
Online Access: | http://iopscience.iop.org/1468-6996/13/1/015009 |