Alzheimer‐related altered white matter microstructural integrity in Down syndrome: A model for sporadic AD?

Alzheimer‐related altered white matter microstructural integrity in Down syndrome: A model for sporadic AD?

Abstract Introduction Virtually all adults with Down syndrome (DS) develop Alzheimer's disease (AD)‐associated neuropathology by the age of 40, with risk for dementia increasing from the early 50s. White matter (WM) pathology has been reported in sporadic AD, including early demyelination, micr...

Full description

Bibliographic Details
Main Authors: H. Diana Rosas, Eugene Hsu, Nathaniel D. Mercaldo, Florence Lai, Margaret Pulsifer, David Keator, Adam M. Brickman, Julie Price, Michael Yassa, Christy Hom, Sharon J. Krinsky‐McHale, Wayne Silverman, Ira Lott, Nicole Schupf
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease
Down syndrome
white matter integrity
Online Access:https://doi.org/10.1002/dad2.12040

Internet

https://doi.org/10.1002/dad2.12040

Similar Items