Maduramicin inhibits proliferation and induces apoptosis in myoblast cells.

Maduramicin, a polyether ionophore antibiotic derived from the bacterium Actinomadura yumaensis, is currently used as a feed additive against coccidiosis in poultry worldwide. It has been clinically observed that maduramicin can cause skeletal muscle and heart cell damage, resulting in skeletal musc...

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Bibliographic Details
Main Authors: Xin Chen, Ying Gu, Karnika Singh, Chaowei Shang, Mansoureh Barzegar, Shanxiang Jiang, Shile Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4274093?pdf=render