A method for validating the accuracy of NMR protein structures

The authors present a method for calculating the accuracy of an NMR structure, where flexibility from backbone chemical shifts is compared to structural flexibility predicted using rigidity theory. The authors validate their method and use it to compare the accuracy of NMR and X-ray structures.

Bibliographic Details
Main Authors: Nicholas J. Fowler, Adnan Sljoka, Mike P. Williamson
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20177-1