CHML promotes liver cancer metastasis by facilitating Rab14 recycle

Metastasis-associated recurrence is a major cause of poor prognosis in hepatocellular carcinoma. Here, the authors show that expression of choroideremia-like (CHML) is elevated and associates with poor prognosis in hepatocellular carcinoma, and mechanistically CHML promotes metastasis in a Rab14-dep...

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Bibliographic Details
Main Authors: Tian-Wei Chen, Fen-Fen Yin, Yan-Mei Yuan, Dong-Xian Guan, Erbin Zhang, Feng-Kun Zhang, Hao Jiang, Ning Ma, Jing-Jing Wang, Qian-Zhi Ni, Lin Qiu, Jing Feng, Xue-Li Zhang, Ying Bao, Kang Wang, Shu-Qun Cheng, Xiao-Fan Wang, Xiang Wang, Jing-Jing Li, Dong Xie
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10364-0