Intimin and invasin export their C-terminus to the bacterial cell surface using an inverse mechanism compared to classical autotransport.

Invasin and intimin are major virulence factors of enteropathogenic Yersiniae and Escherichia coli, mediating invasion into and intimate adherence to host cells, respectively. Several studies have hinted that extracellular portion of these homologous proteins might be exported via an autotransport m...

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Bibliographic Details
Main Authors: Philipp Oberhettinger, Monika Schütz, Jack C Leo, Nadja Heinz, Jürgen Berger, Ingo B Autenrieth, Dirk Linke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23056583/?tool=EBI