Identification of Predictive Markers for Response to Neoadjuvant Chemoradiation in Rectal Carcinomas by Proteomic Isotope Coded Protein Label (ICPL) Analysis

Identification of Predictive Markers for Response to Neoadjuvant Chemoradiation in Rectal Carcinomas by Proteomic Isotope Coded Protein Label (ICPL) Analysis

Neoadjuvant chemoradiation (nCRT) is an established procedure in stage union internationale contre le cancer (UICC) II/III rectal carcinomas. Around 53% of the tumours present with good tumor regression after nCRT, and 8%–15% are complete responders. Reliable selection markers would allow the identi...

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Bibliographic Details
Main Authors: Roland S. Croner, Müzeyyen Sevim, Metodi V. Metodiev, Peter Jo, Michael Ghadimi, Vera Schellerer, Maximillian Brunner, Carol Geppert, Tilman Rau, Michael Stürzl, Elisabeth Naschberger, Klaus E. Matzel, Werner Hohenberger, Friedrich Lottspeich, Josef Kellermann
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:International Journal of Molecular Sciences
Subjects:
rectal cancer
chemoradiation
proteomic
ICPL
Online Access:http://www.mdpi.com/1422-0067/17/2/209

Internet

http://www.mdpi.com/1422-0067/17/2/209

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