Challenges in Stratifying the Molecular Variability of Patient-Derived Colon Tumor Xenografts

Challenges in Stratifying the Molecular Variability of Patient-Derived Colon Tumor Xenografts

Colorectal cancer (CRC) is the second most common cancer in Europe and a leading cause of death worldwide. Patient-derived xenograft (PDX) models maintain complex intratumoral biology and heterogeneity and therefore remain the platform of choice for translational drug discovery. In this study, we im...

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Main Authors: Magdalena Cybulska, Tomasz Olesinski, Krzysztof Goryca, Katarzyna Paczkowska, Malgorzata Statkiewicz, Michal Kopczynski, Aleksandra Grochowska, Katarzyna Unrug-Bielawska, Anita Tyl-Bielicka, Marta Gajewska, Andrzej Mroz, Michalina Dabrowska, Jakub Karczmarski, Agnieszka Paziewska, Leszek Zając, Mariusz Bednarczyk, Michal Mikula, Jerzy Ostrowski
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/2954208

Internet

http://dx.doi.org/10.1155/2018/2954208

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