Transcriptome Profiles of Human Visceral Adipocytes in Obesity and Colorectal Cancer Unravel the Effects of Body Mass Index and Polyunsaturated Fatty Acids on Genes and Biological Processes Related to Tumorigenesis

Transcriptome Profiles of Human Visceral Adipocytes in Obesity and Colorectal Cancer Unravel the Effects of Body Mass Index and Polyunsaturated Fatty Acids on Genes and Biological Processes Related to Tumorigenesis

Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of several pathologies including colorectal cancer (CRC). Although the adipose tissue inflammatory state is now recognized as a key player in obesity-associated morbidities, the underlying biological proc...

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Bibliographic Details
Main Authors: Manuela Del Cornò, Antonella Baldassarre, Enrica Calura, Lucia Conti, Paolo Martini, Chiara Romualdi, Rosaria Varì, Beatrice Scazzocchio, Massimo D'Archivio, Andrea Masotti, Sandra Gessani
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
obesity
body mass index
colorectal cancer
adipocyte
fatty acid
transcriptome
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00265/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00265/full

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