Blood Cell DNA Methylation of Aging-Related Ubiquitination Gene DZIP3 Can Predict the Onset of Early Stage Colorectal Cancer

Blood Cell DNA Methylation of Aging-Related Ubiquitination Gene DZIP3 Can Predict the Onset of Early Stage Colorectal Cancer

There is a body of evidence that the aging immune system is linked to cancer. In this study, with aging- and immune-related DNA methylation data, we investigated the DNA methylation regulation changes in promoters with other regions of genes during aging and their association with the immune-cell pr...

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Bibliographic Details
Main Authors: Yuan Quan, Fengji Liang, Deqing Wu, Xueqing Yao, Zhihuang Hu, Yuexing Zhu, Ying Chen, Andong Wu, Danian Tang, Bingyang Huang, Ruifeng Xu, Zejian Lyu, Qian Yan, Lang Luo, Zhengzhi Ning, Yong Li, Jianghui Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
colon cancer
aging immune system
E3 ubiquitin ligase
liquid biopsy
cancer screening
early detection
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.544330/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.544330/full

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