Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway

Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway

Background: Epirubicin is a first-line chemotherapeutic drug for the clinical treatment of diffuse large B cell lymphoma (DLBCL), but the overexpression of multidrug resistance (MDR) transporter proteins, especially P-glycoprotein (P-gp), renders epirubicin ineffective. Some studies reveal the poten...

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Bibliographic Details
Main Authors: Kaili Liu, Jincheng Song, Yue Yan, Kun Zou, Yuxuan Che, Beichen Wang, Zongjuan Li, Wendan Yu, Wei Guo, Lijuan Zou, Wuguo Deng, Xiuhua Sun
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320303685

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http://www.sciencedirect.com/science/article/pii/S1936523320303685

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