Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer

Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer

Abstract Background Trastuzumab is a drug that targets the receptor tyrosine kinase HER2 and is essential for the treatment of HER2-positive breast cancer. Resistance to the drug leads to severe consequences, including disease recurrence, tumor enlargement, and metastasis. We hypothesized that trast...

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Bibliographic Details
Main Authors: Ami Hori, Masafumi Shimoda, Yasuto Naoi, Naofumi Kagara, Tomonori Tanei, Tomohiro Miyake, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Breast Cancer Research
Subjects:
Breast carcinoma
ERBB2
Salinomycin
Trastuzumab
Vasculogenic mimicry
Online Access:http://link.springer.com/article/10.1186/s13058-019-1167-3

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http://link.springer.com/article/10.1186/s13058-019-1167-3

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