Preclinical evaluation of the antineoplastic action of 5-aza-2'-deoxycytidine and different histone deacetylase inhibitors on human Ewing's sarcoma cells

<p>Abstract</p> <p>Background</p> <p>Most patients with advanced Ewing's sarcoma (EWS) respond poorly to conventional chemotherapy, indicating the need for new treatment approaches. Epigenetic events, such as promoter hypermethylation and chromatin histone deacetyl...

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Bibliographic Details
Main Authors: Bernstein Mark L, Momparler Richard L, Hurtubise Annie
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/8/1/16