Giardia duodenalis extracellular vesicles regulate the proinflammatory immune response in mouse macrophages in vitro via the MAPK, AKT and NF-κB pathways

Giardia duodenalis extracellular vesicles regulate the proinflammatory immune response in mouse macrophages in vitro via the MAPK, AKT and NF-κB pathways

Abstract Background Giardia duodenalis is an extracellular protozoan parasite that causes giardiasis in mammals. The presentation of giardiasis ranges from asymptomatic to severe diarrhea, and the World Health Organization lists it in the Neglected Diseases Initiative. Extracellular vesicles (EVs) a...

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Bibliographic Details
Main Authors: Panpan Zhao, Lili Cao, Xiaocen Wang, Jianhua Li, Jingquan Dong, Nan Zhang, Xin Li, Shan Li, Min Sun, Xichen Zhang, Min Liang, Xudong Pu, Pengtao Gong
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Parasites & Vectors
Subjects:
Giardia duodenalis
Extracellular vesicles
Immune response
MAPK
Online Access:https://doi.org/10.1186/s13071-021-04865-5

Internet

https://doi.org/10.1186/s13071-021-04865-5

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