Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder

<p>Abstract</p> <p>Background</p> <p>The orbitofrontal cortex (OFC) may play a role in the pathogenesis of psychiatric illnesses such as bipolar disorder and schizophrenia, in which hypothalamic-pituitary-adrenal (HPA) axis abnormalities are observed and stress has been...

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Bibliographic Details
Main Authors: Sinclair Duncan, Webster Maree J, Fullerton Janice M, Weickert Cynthia
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Psychiatry
Online Access:http://www.biomedcentral.com/1471-244X/12/84