Chimeric Antigen Receptor Expressing Natural Killer Cells for the Immunotherapy of Cancer

Adoptive cell therapy has emerged as a powerful treatment for advanced cancers resistant to conventional agents. Most notable are the remarkable responses seen in patients receiving autologous CD19-redirected chimeric antigen receptor (CAR) T cells for the treatment of B lymphoid malignancies; howev...

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Bibliographic Details
Main Authors: Rohtesh S. Mehta, Katayoun Rezvani
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00283/full