Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function
Invasive fungal infections remain difficult to treat and require novel targeting strategies. The 12-kDa FK506-binding protein (FKBP12) is a ubiquitously expressed peptidyl-prolyl isomerase with considerable homology between fungal pathogens and is thus a prime candidate for future targeting efforts...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2016-04-01
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| Series: | mBio |
| Online Access: | http://mbio.asm.org/cgi/content/full/7/2/e00492-16 |