Overexpression of the transcribed ultraconserved region Uc.138 accelerates colon cancer progression

Abstract Ultraconserved regions (UCRs) are 481 genomic sequences with 100% identity across humans, rats, and mice. Increasing evidence suggests that non-coding RNAs transcribed from UCRs are involved in various diseases, especially cancers. The human transformer 2β gene (TRA2B) encodes a UCR (uc.138...

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Bibliographic Details
Main Authors: Yuki Kuwano, Kensei Nishida, Kazuhito Rokutan
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88123-9