Assays for quantification of male and female gametocytes in human blood by qRT-PCR in the absence of pure sex-specific gametocyte standards

Assays for quantification of male and female gametocytes in human blood by qRT-PCR in the absence of pure sex-specific gametocyte standards

Abstract Background Malaria transmission from humans to Anopheles mosquitoes requires the presence of gametocytes in human peripheral circulation, and the dynamics of transmission are determined largely by the density and sex ratio of the gametocytes. Molecular methods are thus employed to measure g...

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Bibliographic Details
Main Authors: Claire Y. T. Wang, Emma Ballard, Stacey Llewellyn, Louise Marquart, Teun Bousema, James S. McCarthy, Katharine A. Collins
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Malaria Journal
Subjects:
Malaria
Gametocytes
VIS
CHMI
QRT-PCR
Droplet digital PCR
Online Access:http://link.springer.com/article/10.1186/s12936-020-03291-9

Internet

http://link.springer.com/article/10.1186/s12936-020-03291-9

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