Methylation of migraine-related genes in different tissues of the rat.

17ß-Estradiol, an epigenetic modulator, is involved in the increased prevalence of migraine in women. Together with the prophylactic efficacy of valproate, which influences DNA methylation and histone modification, this points to the involvement of epigenetic mechanisms. Epigenetic studies are often...

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Bibliographic Details
Main Authors: Sieneke Labruijere, Lisette Stolk, Michael Verbiest, René de Vries, Ingrid M Garrelds, Paul H C Eilers, A H Jan Danser, André G Uitterlinden, Antoinette MaassenVanDenBrink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946422?pdf=render