Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia

Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia

Zhenlong Xingnao Capsule (ZXC) is a Tibetan medicine used to treat ischemic stroke. In this study, we determined the in vitro and in vivo effects of ZXC on reactive oxygen species (ROS) in a mouse BV-2 microglial cell hypoxia-reoxygenation and rat middle cerebral artery occlusion infarction models....

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Bibliographic Details
Main Authors: Xia Wei, Qingfen Zhu, Na Liu, Lihua Xu, Sheng Wei, Zhiyun Fan, Changhua Sun, Yan Zhao, Mingqi Qiao, Jibiao Wu, Defu Hu, Yang Wang, Peng Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
Zhenlong Xingnao Capsule
middle cerebral artery occlusion model
cerebral ischemia-reperfusion injury
reactive oxygen species
BV-2 cell
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01096/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01096/full

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