Identification of microRNAs involved in NOD-dependent induction of pro-inflammatory genes in pulmonary endothelial cells.

The nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 are mammalian cytosolic pattern recognition receptors sensing bacterial peptidoglycan fragments in order to initiate cytokine expression and pathogen host defense. Since endothelial cells are relevant cells for pathogen...

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Main Authors: Ann-Kathrin Vlacil, Evelyn Vollmeister, Wilhelm Bertrams, Florian Schoesser, Raghav Oberoi, Jutta Schuett, Harald Schuett, Sonja Huehn, Katrin Bedenbender, Bernd T Schmeck, Bernhard Schieffer, Karsten Grote
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228764