Cardiac Myocytes Ca2+ and Na+ Regulation in Normal and Failing Hearts

Abstract.: Ca2+ is a central player in the excitation-contraction coupling of cardiac myocytes, the process that enables the heart to contract and relax. Mishandling of Ca2+ is a central cause of both contractile dysfunction and arrhythmias in pathophysiological conditions such as heart failure (HF)...

Full description

Bibliographic Details
Main Authors: Donald M. Bers, Sanda Despa
Format: Article
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access: