The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease

The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease

The macrophage-inducible C-type lectin (mincle) is part of the innate immune system and acts as a pattern recognition receptor for pathogen-associated molecular patterns (PAMPS) and damage-associated molecular patterns (DAMPs). Ligand binding induces mincle activation which consequently interacts wi...

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Bibliographic Details
Main Authors: Robert Schierwagen, Frank E. Uschner, Cristina Ortiz, Sandra Torres, Max J. Brol, Olaf Tyc, Wenyi Gu, Christian Grimm, Stefan Zeuzem, Andreas Plamper, Philipp Pfeifer, Sebastian Zimmer, Christoph Welsch, Liliana Schaefer, Karl P. Rheinwalt, Joan Clària, Vicente Arroyo, Jonel Trebicka, Sabine Klein
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
ACLF
bacterial translocation
fibrosis
inflammation
NASH
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01352/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01352/full

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