Immunometabolic Activation of Invariant Natural Killer T Cells

Immunometabolic Activation of Invariant Natural Killer T Cells

Invariant natural killer T (iNKT) cells are lipid-reactive T cells with profound immunomodulatory potential. They are unique in their restriction to lipid antigens presented in CD1d molecules, which underlies their role in lipid-driven disorders such as obesity and atherosclerosis. In this review, w...

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Bibliographic Details
Main Authors: Francesca A. Ververs, Eric Kalkhoven, Belinda van’t Land, Marianne Boes, Henk S. Schipper
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
immunometabolism
NKT
obesity
atherosclerosis
sphingolipid
AMPK
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01192/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01192/full

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