Decoding high Gonadotropin-releasing hormone pulsatility: a role for GnRH receptor coupling to the cAMP pathway?

Decoding high Gonadotropin-releasing hormone pulsatility: a role for GnRH receptor coupling to the cAMP pathway?

The GnRH pulsatile pattern is critical for appropriate regulation of gonadotrope activity but only little is known about the signaling mechanisms by which gonadotrope cells decode such pulsatile pattern. Here, we review recent lines of evidence showing that the GnRH receptor (GnRH-R) activates the c...

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Bibliographic Details
Main Authors: Joelle eCohen-Tannoudji, Charlotte eAvet, Ghislaine eGarrel, raymond eCounis, Violaine eSimon
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Endocrinology
Subjects:
Pituitary
GnRH receptor
GnRH pulsatile pattern
gonadotrope cell signaling
cAMP pathway.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00107/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00107/full

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