NLRP3 inhibition attenuates early brain injury and delayed cerebral vasospasm after subarachnoid hemorrhage
Abstract Background The NLRP3 inflammasome is a critical mediator of several vascular diseases through positive regulation of proinflammatory pathways. In this study, we defined the role of NLRP3 in both the acute and delayed phases following subarachnoid hemorrhage (SAH). SAH is associated with dev...
Main Authors: | William S. Dodd, Imaray Noda, Melanie Martinez, Koji Hosaka, Brian L. Hoh |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-021-02207-x |
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