Plasma-Derived Fibronectin Stimulates Chondrogenic Differentiation of Human Subchondral Cortico-Spongious Progenitor Cells in Late-Stage Osteoarthritis

Plasma-Derived Fibronectin Stimulates Chondrogenic Differentiation of Human Subchondral Cortico-Spongious Progenitor Cells in Late-Stage Osteoarthritis

Migration and chondrogenesis of human subchondral cortico-spongious progenitor cells (SPCs) are the key steps in the repair of microfracture-induced articular cartilage defects. The aim of this study was to evaluate the effect of human plasma-derived fibronectin (Fn) on the chondrogenic differentiat...

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Bibliographic Details
Main Authors: Chao Jiang, Pei Ma, Bupeng Ma, Zhihong Wu, Guixing Qiu, Xinlin Su, Zenan Xia, Zixing Ye, Yipeng Wang
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
plasma-derived fibronectin
cartilage regeneration
chondrogenesis
subchondral progenitor cells
Online Access:http://www.mdpi.com/1422-0067/16/8/19477

Internet

http://www.mdpi.com/1422-0067/16/8/19477

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