Modeling and Manipulating Human Diseases with Induced Pluripotent Stem Cells, Pig Models and Precision Gene Editing.
We have developed systems, e.g. C-Check, that can be used to rapidly select and quantify CRISPR/Cas9 nuclease activity and enrichment of genetically modified cells with desired mutations (Zhou et al., 2016). To facilitate the simultaneous manipulation of multiple genes in cells, we have developed a...
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| Format: | Article |
| Language: | English |
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Università degli Studi di Milano
2016-06-01
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| Series: | International Journal of Health, Animal Science and Food Safety |
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| Online Access: | http://riviste.unimi.it/index.php/haf/article/view/7234 |