Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection.

The identification of a new generation of potent broadly neutralizing HIV-1 antibodies (bnAbs) has generated substantial interest in their potential use for the prevention and/or treatment of HIV-1 infection. While combinations of bnAbs targeting distinct epitopes on the viral envelope (Env) will li...

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Bibliographic Details
Main Authors: Kshitij Wagh, Tanmoy Bhattacharya, Carolyn Williamson, Alex Robles, Madeleine Bayne, Jetta Garrity, Michael Rist, Cecilia Rademeyer, Hyejin Yoon, Alan Lapedes, Hongmei Gao, Kelli Greene, Mark K Louder, Rui Kong, Salim Abdool Karim, Dennis R Burton, Dan H Barouch, Michel C Nussenzweig, John R Mascola, Lynn Morris, David C Montefiori, Bette Korber, Michael S Seaman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4814126?pdf=render