LCQS: an efficient lossless compression tool of quality scores with random access functionality

Abstract Background Advanced sequencing machines dramatically speed up the generation of genomic data, which makes the demand of efficient compression of sequencing data extremely urgent and significant. As the most difficult part of the standard sequencing data format FASTQ, compression of the qual...

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Bibliographic Details
Main Authors: Jiabing Fu, Bixin Ke, Shoubin Dong
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3428-7