Signaling of Macrophage Inflammatory Protein (MIP)-3β Facilitates Dengue Virus-Induced Microglial Cell Migration

Signaling of Macrophage Inflammatory Protein (MIP)-3β Facilitates Dengue Virus-Induced Microglial Cell Migration

The infection by dengue virus (DENV) of microglia causes cell activation and migration via a mechanism involving viral entry, RNA release, and Toll-like receptor 3 signaling. In this study, we demonstrated that secreted chemotactic factors present in microglial conditioned medium (MCM) facilitated c...

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Bibliographic Details
Main Authors: Ming-Kai Jhan, Ting-Jing Shen, Po-Chun Tseng, Yung-Ting Wang, Chiou-Feng Lin
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Viruses
Subjects:
dengue virus
microglia
migration
caveolae
MIP-3β
Online Access:https://www.mdpi.com/1999-4915/10/12/690

Internet

https://www.mdpi.com/1999-4915/10/12/690

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