ALOX5AP Predicts Poor Prognosis by Enhancing M2 Macrophages Polarization and Immunosuppression in Serous Ovarian Cancer Microenvironment

ALOX5AP Predicts Poor Prognosis by Enhancing M2 Macrophages Polarization and Immunosuppression in Serous Ovarian Cancer Microenvironment

BackgroundSerous ovarian cancer (SOC) is a highly lethal gynecological malignancy with poor prognosis. Given the importance of the immune-related tumor microenvironment (TME) in ovarian cancer, investigating tumor-immune interactions and identifying novel prognostic and therapeutic targets in SOC is...

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Bibliographic Details
Main Authors: Xiang Ye, Limei An, Xiangxiang Wang, Chenyi Zhang, Wenqian Huang, Chenggong Sun, Rongrong Li, Hanlin Ma, Hongyan Wang, Min Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
targeted therapy
serous ovarian cancer
ALOX5AP
immunosuppression
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.675104/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.675104/full

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