Dual targeting of insulin and venus kinase Receptors of Schistosoma mansoni for novel anti-schistosome therapy.

BACKGROUND: Chemotherapy of schistosomiasis relies on a single drug, Praziquantel (PZQ) and mass-use of this compound has led to emergence of resistant strains of Schistosoma mansoni, therefore pointing out the necessity to find alternative drugs. Through their essential functions in development and...

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Bibliographic Details
Main Authors: Mathieu Vanderstraete, Nadège Gouignard, Katia Cailliau, Marion Morel, Julien Lancelot, Jean-François Bodart, Colette Dissous
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3656120?pdf=render