Absence of the c.169+50delTAAACAG mutation of SOD1 gene in a sample of keratoconus patients in Brazilian population

Absence of the c.169+50delTAAACAG mutation of SOD1 gene in a sample of keratoconus patients in Brazilian population

Abstract Objective To determine the presence of the 7-bp deletion c.169+50delTAAACAG in intron 2 of Superoxide Dismutase-1 gene in keratoconic patients from the State of São Paulo, Brazil, which promotes splicing variations, resulting in non-functional Superoxide Dismutase-1 antioxidant proteins, wh...

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Bibliographic Details
Main Authors: Alessandro Garcia Lopes, Gildásio Castello de Almeida Júnior, Ronan Marques Teixeira, Luiz Carlos de Mattos, Cinara Cássia Brandão de Mattos, Lilian Castiglioni
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Research Notes
Subjects:
Keratoconus
Cornea
Superoxide Dismutase-1 gene
Corneal Diseases
Polymorphism
Genetic
Online Access:http://link.springer.com/article/10.1186/s13104-020-05166-3

Internet

http://link.springer.com/article/10.1186/s13104-020-05166-3

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